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ADAPTED2: Mobile Care for Pain After Childhood Cancer

About this study

Some childhood cancer survivors have pain that lasts long after treatment ends. This lasting (chronic) pain can make it hard to go to school, spend time with friends, or enjoy daily life. We are studying new ways to help survivors manage their pain without relying on medicine.

This study includes children and teens who had childhood cancer and have ongoing pain. It also includes patients with other diseases who had treatments often used for cancer treatment (such as chemotherapy, surgery, or radiation therapy).  

Usual care for long-term pain may include education, medicine, or cognitive behavioral therapy (CBT). CBT is a type of therapy that teaches people how to change the way they think about and react to pain. It is usually done in person, but the research team has created a mobile app that can be accessed on a mobile phone or tablet. The CBT App has been designed to work well for people from different backgrounds.

Participants will be randomly placed into 1 of 2 groups. One group will use the CBT App for 6 weeks. It includes lessons on:

  • Pain education
  • Stress and emotions
  • Relaxation
  • Healthy lifestyle
  • Staying active
  • Preventing relapse 

The other group will meet with a study team member each week to review educational materials about pain. These materials explain what chronic pain is, how it is treated, and ways to cope with it. This group will have access to the CBT App after the study ends.

Patients and their parents or caregivers will answer questionnaires at the start of the study, after 6 weeks, and 3 months later. These questions will ask about pain, mood, sleep, and other symptoms. Each set of questionnaires takes about 30 minutes to complete.

This study could lead to new tools, like mobile apps and easy-to-use education materials, that help survivors feel better, stay active, and enjoy daily life.

Eligibility overview

  • 10–17 years old
  • Childhood cancer survivor or had cancer-type treatments (such as those for Langerhans cell histiocytosis) 
  • At least 1 year after treatment has ended 
  • Pain present for 3 months or longer 
  • Pain interferes with at least 1 area of daily living
  • Patient’s parent or caregiver is at least 18 years old 

Request a referral

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

ADAPTED2: Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

Study goal:

To test whether a mobile cognitive behavioral therapy (CBT) App or education materials can help manage chronic pain in childhood cancer survivors.

Diagnosis:

Childhood cancer, Langerhans cell histiocytosis

Age:

10–17 years old

Clinical trial categories:

Childhood Cancer Langerhans Cell Histiocytosis

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

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