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COPILOT: Interventions for Early Aging in Cancer

About this study

Childhood cancer survivors age faster than their peers. This happens because of both their cancer diagnosis and cancer treatment. Early aging is linked to physical, cognitive (memory and attention), and emotional health problems.

The St. Jude Lifetime Cohort Study (SJLIFE)  has created several interventions designed to remedy these problems and help slow early aging. Regular exercise, brain training, and mindfulness practice will help improve function when done on their own. But we would like to see if combining these activities would help even more.

In this new study, researchers will find out if SJLIFE childhood cancer survivors are able to do 2 interventions together to prevent early aging. Participants will do exercises and either brain-training activities or mindfulness training. They will do this for 12 weeks at home. The study will compare 2 groups: one that does exercise and brain-training, and the other that does exercises and mindfulness.

During the study, participants will answer questions, take online tests to see how well they think and feel, and do fitness testing. Everyone will be asked to exercise 3 times per week with the help of a coach and videos, and either complete brain training on the computer or verbally guided mindfulness training, also with the help of a coach.

Participants will answer questions, take online tests to see how well they think and feel, and do fitness testing. After 12 weeks, they will be asked for their opinions on taking part in the interventions.

This study is important because it could lead to programs that improve survivors’ memory, focus, and overall well-being.

Eligibility overview

  • Age 18 years and up
  • Enrolled in the SJLIFE study
  • Not active, and has trouble with paying attention or handling feelings

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

COPILOT: Complementary behavioral interventions to remediate cognitive impairment or emotional distress in cancer survivors

Study goal:

To study if adult cancer survivors are able to do 2 interventions (exercise and cognitive training or mindfulness) that may prevent or reverse early aging.

Diagnosis:

Childhood cancer

Age:

18 years and up

Clinical trials categories:

Childhood Cancer

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

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