About this study
Leukemia is a cancer of the blood cells. It is the most common childhood cancer. Treatment may include radiation and strong cancer medicine, also known as chemotherapy. These treatments can sometimes cause children to develop problems with learning, behavior and social skills later in life.
Down syndrome is a condition that is caused by changes in the body’s genes. Children with Down syndrome can have a harder time learning. They also have a higher risk of developing leukemia.
This study will focus on childhood leukemia survivors with Down syndrome. Researchers will ask survivors to take a test to see what kinds of learning, behavior and social problems they may have. Researchers will also ask parents questions about their children’s learning and behavior. The study will take about two hours for survivors and their parents to complete. Researchers hope the study will help other children with leukemia and Down syndrome in the future.
Purpose of this clinical trial
The main goal of this study is to learn about thinking, learning, behavior and social functioning in childhood leukemia survivors with Down syndrome.
Eligibility overview
- St. Jude Children’s Research Hospital patient with acute leukemia (i.e., ALL or AML)
- Trisomy 21 Down syndrome diagnosis
- Completed all cancer therapy at St. Jude since 1980 and at least six months prior to study visit
- English as the primary language