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FITHOD: Exercise Study for Hodgkin Lymphoma Survivors

About this study

Children, teens, and young adults who survive Hodgkin lymphoma may have health problems later. These can include late effects that affect the heart, lungs, muscles, and nerves. This can make it harder to stay active and feel strong. Researchers want to find safe ways to help survivors stay active  and healthy. This study looks at whether a type of exercise called HIIT may help.

HIIT stands for high-intensity interval training. With HIIT training, there are short times of hard exercise alternating with recovery. HIIT has helped adults with cancer and people without cancer improve their fitness. We do not know if HIIT works well for young people who have recently finished Hodgkin lymphoma treatment. This study will help us learn whether this kind of exercise is a good choice for these survivors.

People in the study will do HIIT workouts 3 times a week for 12 weeks. Each workout lasts about 25 minutes. It includes:

  • A warm-up
  • Short, hard exercise
  • Recovery
  • Cool-down

Workouts are done at home with live help from an exercise expert using an iPad. Participants can choose activities like walking, biking, or running. They will also take surveys with short questions about how the workouts feel and what makes exercise easier or harder.

Researchers will test how fit people are both before and after the study. Participants will also do tests to look at  body strength, movement, nerve problems (neuropathy), and daily activity. These will include blood tests of aging markers and a nerve test. 

The main goal is to learn if this exercise program is easy to follow after treatment and if it can improve survivors’ fitness. If it works well, HIIT could be tested in larger to studies to see whether it can improve long-term heart health in survivors.

Eligibility overview

  • 10–24 years old
  • Had Hodgkin lymphoma as a child, teen, or young adult
  • Finished Hodgkin lymphoma treatment within the past 2 years
  • Medically cleared by a doctor to take part in exercise
  • Not currently doing high‑intensity interval training

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The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

FITHOD: Feasibility of High Intensity Interval Training in Survivors of Childhood, Adolescent, and Young Adult Hodgkin Lymphoma

Study goal:

To study whether high-intensity interval exercise is feasible for young survivors of Hodgkin lymphoma.

Diagnosis:

Hodgkin lymphoma

Age:

10–24 years

Clinical trial categories:

Hodgkin Lymphoma

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

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