Skip to Main Content
Recruiting

PACTPAT: Safer Cell Therapies for Childhood Cancer

About this study

Many childhood cancer survivors have lasting side effects from treatments like chemotherapy, radiation, and surgery. These treatments can harm healthy cells as well as cancer cells. Scientists want to find safer ways to treat cancer that cause fewer side effects.

The PACTPAT clinical trial is studying blood from children and young adults with cancer. We want to learn how immune cells in the blood can be used to treat cancer in a smarter and safer way. This could lead to better treatments in the future.

Patients who join the study will be asked to donate a small amount of blood. Blood may be taken from a vein in the arm or from a central line, if the patient already has one. If a needle stick is needed, it will be done at the same time as routine blood tests, so no extra needle stick is required. Central-line blood draws will also be done at the same time as routine blood tests.

Some patients may be asked for a second sample at least 8 weeks later, but this is optional.

Blood samples will be used only for research in the lab. Scientists will study how immune cells work and how they might be strengthened to better attack cancer cells. To protect privacy, samples will be labeled with a code, and no personal medical information will be used. Samples will be stored for up to 1 year and then destroyed.

Participation in this study is voluntary and does not directly benefit patients. But by  taking part, patients may help researchers discover safer, more effective ways to treat cancer in the future.  

Eligibility overview

  • Patients of any age who are receiving care for childhood cancer at St. Jude
  • Enrolled in TBANK study

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

PACTPAT: Preclinical Assessment of Cell Therapies – Patient Samples

Study goal:

To study how immune cells from children and young adults with cancer can be used to create safer, more effective cell therapies.

Age:

Infants to adults

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

Learn more