About this study
CAR T–cell therapy is a treatment that uses the patient’s own immune cells to fight cancer. We need to learn more about the side effects that may happen a long time after this treatment ends. The PROSPER study will help doctors learn more about these long-term side effects.
Patients in this study will have data collected during their regular check-ups. This includes blood and bone marrow samples. They will also be asked to fill out surveys about how they feel, how well they can do their usual activities, and any symptoms they may have. Information will be collected at 3 months, 6 months, 1 year, and 2 years after CAR T–cell therapy is given.
Researchers will study intermediate and long-term side effects. They want to know how often patients get infections, how well their blood cell counts recover, and if the CART-T cell therapy causes any problems with the nervous system.
Learning about side effects that happen months or years after CAR T–cell therapy helps doctors find better ways to care for patients as they recover. Results of this study may also help doctors create better treatments in the future and help patients and families make informed decisions. This research could lead to safer therapies and better results for children, teens, and young adults with cancer.
Eligibility overview
- Up to 30 years old
- Have had a CAR T–cell infusion within the past 1–3 months