About this study
Lymph nodes are small glands that help fight infections, but they can also be places where cancer spreads. In some childhood cancers, removing affected lymph nodes is important for staging and treatment. Right now, doctors find lymph nodes by looking for them and feeling for them during surgery. The VISCERALx clinical trial will test a new way to see lymph nodes that drain tumors inside the abdomen (belly).
A dye called indocyanine green (ICG) can make lymph nodes glow under a special kind of light. We want to find out if using ICG makes it easier to see the lymph nodes that should be removed. The study will also test if ICG may help surgeons find cancer that has spread to lymph nodes outside of where they suspect the cancer lies.
During surgery, the patient will receive the ICG dye through an IV. The dye will help the doctor see which lymph nodes need to be removed. After surgery, the removed lymph nodes will be examined to see if they contain cancer. Patients will be watched for 24 hours after surgery to check for any side effects from the dye.
If this study is successful, it could make lymph node surgery more precise, helping doctors remove cancer while protecting healthy tissue. This could lead to better outcomes for children and teens with solid tumors.
Eligibility overview
- 0–20 years old
- Kidney tumor
- Para-testicular rhabdomyosarcoma (rhabdomyosarcoma that develops around the testicles) in boys older than 10 years