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Sickle Cell Disease Clinical Trials

Open clinical trials for sickle cell disease

Recruiting
CASPERKID: Study of Exa-cel in Children with Severe Sickle Cell Disease

Study goal:

The main goal of this study is to see if a single dose of exa-cel allows your child’s body to increase the amount of hemoglobin F while reducing the painful effects of sickle cell disease.

Age:

2 to 11 years old

Recruiting
SCCRIP: Sickle Cell Research and Intervention Program

Study goal:

The purpose of this research study is to collect data on sickle cell disease participants from birth to end of life. With these data, researchers will better understand problems caused by sickle cell disease both in children and in adults. 

Recruiting
LEAPS: Understanding Sickle Cell Disease Transition to Adult Care

Study goal:

The main goal of this study is to find out what a successful health care transition looks like and to look at connections between health care transition and factors such as hospitalizations, patients’ disease knowledge and general adjustment. Researchers also want to know how these factors change over time.

Age:

16 to 20 years old

Recruiting
BHEEM: Study of BEAM-101 in Patients with Severe Sickle Cell Disease

Study goal:

The main goal of this study is to see if a single dose of BEAM-101 allows your body to increase the amount of hemoglobin F while reducing the painful effects of sickle cell disease.

Age:

18 to 35 years old

Recruiting
PMVOCVR: Virtual Reality Therapy for Vaso-Occlusive Crisis in Patients with Sickle Cell Disease

Study goal:

The main goal of this clinical trial is to find out how well virtual reality therapy lessens acute pain in sickle cell patients.

Age:

Between 6 and 25 years old

Recruiting
NCBP01: Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the NCBP for Unrelated Transplantation

Study goal:

The primary purpose of this study is to examine the safety of administration of the unlicensed investigational NCBP HPC-CORD BLOOD products in a multi-institution setting.

Recruiting
INSIGHT-HD: Investigating the Genetics of Blood Disorders

Study goal:

The main goal of this trial is to collect DNA from individuals with non-cancerous blood diseases and their family members. Researchers will use the DNA to study how genes cause and influence these diseases. All research data will be confidential.

Recruiting
SKITS2: School Readiness Intervention for Sickle Cell Disease

Study goal:

This study will help us find out how to make the intervention program better and test it with a larger group of caregivers and their children.

Age:

4–6

Recruiting
SCDSTEMM: Improving Stem Cell Collection in Sickle Cell Disease

Study goal:

To see if motixafortide is safe and helps increase collection of stem cells in adults with sickle cell disease. Learn more about the study.

Age:

Age 18 and older