Immune Disorders Clinical Trials

Full title:

A Registry for Hemophagocytic Lymphohistiocytosis (HLH)

Study goal:

The main goal of the study is to create an international database of HLH patient information. This information will help researchers develop clinical trials in the future on new HLH treatments.

Diagnosis:

Hemophagocytic Lymphohistiocytosis

Full title:

National Marrow Donor Program: A Research Database for Allogeneic Unrelated Hematopoietic Stem Cell Transplantation

Study goal:

The purpose of this study is to collect information from the medical records of patients receiving an unrelated transplant. Information in this research database may be helpful towards improving the results of future patients receiving transplants.

Full title:

Positron Emission Tomography (PET) Contract Agent Kinetics and Safety: [18F]-Fluoromannitol (PAKMANN)

Study goal:

To study the tolerance and safety of [18F]-fluoromannitol in healthy adult volunteers and to see how the tracer moves through their bodies.

Diagnosis:

Healthy volunteer 

Age:

18–75 years old

Full title:

PGEN5: Pharmacogenetic Determinants of Treatment Response in Children

Study goal:

To study genetic (pharmacogenetic) differences in how people process and respond to drugs (agents) in children with childhood cancer or other life-threatening conditions

Diagnosis:

Childhood cancer, Blood disorders, Immune disorders, Infectious diseases, Neurological disorders, Genetic syndromes

Age:

Children and adults

Full title:

TBANK: Protocol for Collecting, Banking, and Distributing Human Tissue Samples: St. Jude Children’s Research Hospital Biorepository

Study goal:

To provide a high-quality repository of tumor and normal samples to facilitate translational research performed by St Jude faculty and their collaborators

Diagnosis:

All diseases

Full title:

VIPER: Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients 

Study goal:

To study respiratory viruses in transplant patients to predict infection risk and improve care

Diagnosis:

Childhood cancer, Blood disorders, Immune disorders, Genetic syndromes

Age:

0–17 years

Full title:

VSTHCT: Haploidentical Viral-Specific T-Cells for Treatment of Cytomegalovirus and Adenovirus Infections after Hematopoietic Cell Transplantation

Study goal:

To study virus-specific T-cells for treating cytomegalovirus and adenovirus infections after hematopoietic cell transplantation

Diagnosis:

Childhood cancer, blood disorders, genetic syndromes, immune disorders, infectious diseases

Age:

Up to 18 years