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Solid Tumor Treatment Team
The Solid tumor treatment team evaluates and treats many types of cancers in children. The tumors they focus on could be in bones, muscles or other tissue, or organs such as the kidneys.
You will always have a primary doctor, your oncologist, who will give updates to your family. Members of your child or teen’s treatment team will have different specialties. This approach gives kids with cancer the best chance of survival and the best possible quality of life.
Director
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Sara M. Federico, MD
Member, St. Jude Faculty
Director, Solid Tumor Division
Sara M. Federico, MD
Member, St. Jude Faculty
Director, Solid Tumor Division
Affiliations
Research Interests
- Clinical investigation of pediatric soft tissue sarcomas
- Translational research in pediatric solid tumor malignancies
- Novel drug development for pediatric solid tumor malignancies
Contact Information
Sara M. Federico, MD
Solid Tumor
MS 260, Room C6016
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Solid Tumor Team Physicians
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Christopher DeRenzo, MD, MBA
Associate Member, St. Jude Faculty
Christopher DeRenzo, MD, MBA
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Adoptive cell therapy for pediatric patients with solid tumors
- Overcoming obstacles to success for clinical implementation of CAR T-cell therapy for pediatric patients with solid and central nervous system (CNS) tumors
Contact Information
Christopher DeRenzo, MD, MBA
Bone Marrow Transplantation and Cellular Therapy
MS 310, Room I4304
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Adam D. Durbin, MD, PhD
Assistant Member, St. Jude Faculty
Adam D. Durbin, MD, PhD
Assistant Member, St. Jude Faculty
Research Interests
- Epigenetic and transcriptional regulation of high-risk pediatric cancers, including neuroblastoma and rhabdomyosarcoma
- Chemical biology and functional genomic perturbation of cancer systems biology
- Drug discovery for pediatric high-risk tumors
- Pathogenesis and modeling of rare tumors
Contact Information
Adam D. Durbin, MD, PhD
Molecular Oncology
MS 353, Room D5062F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paola Friedrich, MD, MPH
Associate Member, St. Jude Faculty
Director, Mexico Region, St. Jude Global
Paola Friedrich, MD, MPH
Associate Member, St. Jude Faculty
Director, Mexico Region, St. Jude Global
Affiliations
Research Interests
- Omproving childhood cancer outcomes in low-and middle-income countries through focus on metrics, health systems, and priority-setting
- Developing resource-level tiered systems in global pediatric oncology, resembling the well-established neonatal intensive care and trauma center levels
- Determining the role of social determinants of health as drivers of outcome disparities between populations in order to identify and address them
- Optimizing treatment for children, adolescents and young adults with solid tumors
Contact Information
Paola Friedrich, MD, MPH
Global Pediatric Medicine
MS 721, Room L1600.15
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jessica Gartrell, MD
Assistant Member, St. Jude Faculty
Jessica Gartrell, MD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Developing early phase clinical trials that lead to the identification of therapeutic biomarkers and novel combination therapies for high risk sarcomas and liver tumors
Contact Information
Jessica Gartrell, MD
Solid Tumor
MS 260, Room C6006
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Dylan Graetz, MD, MPH
Assistant Member, St. Jude Faculty
Director, Culture and Communication
Dylan Graetz, MD, MPH
Assistant Member, St. Jude Faculty
Director, Culture and Communication
Affiliations
Research Interests
- Global pediatric oncology
- Pediatric cancer communication
- Patient-centered care
- Pediatric solid tumors
Contact Information
Dylan Graetz, MD, MPH
Global Pediatric Medicine
MS 721, Room O4025
St. Jude Children's Research Hospital
Memphis, TN 38105-3678
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Lillian Macrae Guenther, MD
Assistant Member, St. Jude Faculty
Lillian Macrae Guenther, MD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Biologic investigation of novel dependency genes in pediatric osteosarcoma
- DNA damage repair mechanisms in pediatric osteosarcoma
- Development of novel therapeutic strategies for pediatric bone sarcomas
- Applications of genomic and chemical screening to identify targeted combinations in pediatric bone sarcomas
Contact Information
Lillian Macrae Guenther, MD
Molecular Oncology
MS 353, Room D5062D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mark E. Hatley, MD, PhD
Associate Member, St. Jude Faculty
Director, Division of Molecular Oncology
Mark E. Hatley, MD, PhD
Associate Member, St. Jude Faculty
Director, Division of Molecular Oncology
Affiliations
Research Interests
- Cellular and molecular origins of embryonal rhabdomyosarcoma
- MicroRNAs in pediatric sarcomas
- Mouse models of pediatric sarcomas
- Development of novel therapies for pediatric sarcomas
Contact Information
Mark E. Hatley, MD, PhD
Molecular Oncology
MS 354, Room D5048F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Sara Helmig, MD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Pediatric solid tumors
- Quality improvement and clinical operations
Contact Information
Sara Helmig, MD
Solid Tumor Division
MS 260, Room C6076
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Catherine G. Lam, MD, MPH
Associate Member, St. Jude Faculty
Director, Asia Pacific Region, St. Jude Global
Director, Health Systems Unit
Co-Director, WHO Collaborating Centre for Childhood Cancer
Catherine G. Lam, MD, MPH
Associate Member, St. Jude Faculty
Director, Asia Pacific Region, St. Jude Global
Director, Health Systems Unit
Co-Director, WHO Collaborating Centre for Childhood Cancer
Affiliations
Research Interests
- Pediatric hematology-oncology in resource-limited settings: evaluating outcomes, applying quality improvement efforts and implementing best practices
- Improving patient outcomes by addressing timely diagnosis, treatment abandonment and palliative care needs
- Advancing outcomes in rare solid tumors, including adrenocortical tumors and nasopharyngeal carcinoma
- Health disparities research; health literacy and patient education
- Optimizing treatment and research for children, adolescents and young adults with solid tumors
Contact Information
Catherine G. Lam, MD, MPH
Oncology
MS 721, Room S2014B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Carlos Rodriguez-Galindo, MD
Member, St. Jude Faculty
Executive Vice President
Chair, Department of Global Pediatric Medicine
Director, St. Jude Global
Co-Associate Director, Outreach, Comprehensive Cancer Center
Four Stars of Chicago Endowed Chair in International Pediatric Outreach
Carlos Rodriguez-Galindo, MD
Member, St. Jude Faculty
Executive Vice President
Chair, Department of Global Pediatric Medicine
Director, St. Jude Global
Co-Associate Director, Outreach, Comprehensive Cancer Center
Four Stars of Chicago Endowed Chair in International Pediatric Outreach
Affiliations
Research Interests
- Global medicine
- Pediatric solid tumors
Contact Information
Carlos Rodriguez-Galindo, MD
Global Pediatric Medicine
MS 721, Room S2015
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Alberto Pappo, MD
Member, St. Jude Faculty
Co-Leader, Developmental Biology & Solid Tumor Program
Alvin Mauer Endowed Chair
Alberto Pappo, MD
Member, St. Jude Faculty
Co-Leader, Developmental Biology & Solid Tumor Program
Alvin Mauer Endowed Chair
Affiliations
Research Interests
Development of novel therapies for pediatric solid tumors with special interest in:
- Pediatric melanoma
- Soft tissue sarcomas
- Pediatric gastrointestinal stromal tumors
Contact Information
Alberto Pappo, MD
Solid Tumor
MS 260, Room C6017
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Victor M. Santana, MD
Member, St. Jude Faculty
Charles B. Pratt Endowed Chair in Solid Tumor Research
Associate Dean, Clinical Investigations MS Program
Director, Global Research Unit, St. Jude Global Alliance
Victor M. Santana, MD
Member, St. Jude Faculty
Charles B. Pratt Endowed Chair in Solid Tumor Research
Associate Dean, Clinical Investigations MS Program
Director, Global Research Unit, St. Jude Global Alliance
Affiliations
Research Interests
- Phase I clinical studies
- Therapy of neuroblastoma
- Role of autologous marrow transplant in pediatric malignancies
- Research ethics
Contact Information
Victor M. Santana, MD
Global Pediatric Medicine
MS 721, Room O3033
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Elizabeth A. Stewart, MD
Associate Member, St. Jude Faculty
Elizabeth A. Stewart, MD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- High-risk pediatric solid tumors
- Development of patient-derived orthotopic solid tumor xenografts
- Translational preclinical testing of novel therapeutics for pediatric solid tumors
Contact Information
Elizabeth A. Stewart, MD
Oncology
MS 324, Room D2038G
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Surgeons
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Andrew M. Davidoff, MD
Member, St. Jude Faculty
Chair, Surgery Department
Director, Surgical Research
St. Jude Endowed Chair in Surgical Research
Andrew M. Davidoff, MD
Member, St. Jude Faculty
Chair, Surgery Department
Director, Surgical Research
St. Jude Endowed Chair in Surgical Research
Affiliations
Research Interests
- Developing new strategies to treat pediatric solid tumors, with a focus on neuroblastoma, using angiogenesis inhibition and gene therapy
- Investigating gene therapy-mediated delivery of angiogenesis inhibitors for long-term cancer treatment in pediatric tumor models
- Advancing gene transfer approaches for monogenetic disorders, particularly hemophilia, using adeno-associated virus vectors
- Conducting preclinical and clinical studies to evaluate the safety and efficacy of gene therapy interventions
Contact Information
Andrew M. Davidoff, MD
Surgery
MS 133, Room B3019
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Andrew Jackson Murphy, MD
Associate Member, St. Jude Faculty
Chief, General Pediatric Surgery Division
Andrew Jackson Murphy, MD
Associate Member, St. Jude Faculty
Chief, General Pediatric Surgery Division
Affiliations
Research Interests
- Pediatric surgical oncology
- Unfavorable histology and treatment-resistant Wilms tumor
- Wilms tumorigenesis
- Cancer stem cells
Contact Information
Andrew Jackson Murphy, MD
Surgery
MS 133, Room IA2305
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Michael D. Neel, MD
Chief, Orthopedic Division, Surgery Department
OrthoMemphis, PC
Michael D. Neel, MD
Chief, Orthopedic Division, Surgery Department
OrthoMemphis, PC
Affiliations
Contact Information
Michael D. Neel, MD
/content/web-sites/research-redesign/en-us/departments/surgery/orthopedic-surgery
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Lindsay J. Talbot, MD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Immunologic profiles of sarcoma primary and metastatic sites
- Immunotherapy strategies, including CAR T-cell therapy, against osteosarcoma and other solid tumors
- Role of chemokine-mediated homing of CAR T-cells in improving treatment efficacy in osteosarcoma and solid tumors
Contact Information
Lindsay J. Talbot, MD
Surgery
MS 133, Room I4306
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Matthew W. Wilson, MD
Chief, Ophthalmology Division, Surgery Department
St. Jude Chair in Pediatric Ophthalmology
University Clinical Health
Full Professor, Department of Ophthalmology, University of Tennessee, Memphis
Matthew W. Wilson, MD
Chief, Ophthalmology Division, Surgery Department
St. Jude Chair in Pediatric Ophthalmology
University Clinical Health
Full Professor, Department of Ophthalmology, University of Tennessee, Memphis
Affiliations
Contact Information
Matthew W. Wilson, MD
Basic Research
Basic scientists
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Taosheng Chen, PhD, PMP
Member, St. Jude Faculty
Director, High Throughput Bioscience Center
Taosheng Chen, PhD, PMP
Member, St. Jude Faculty
Director, High Throughput Bioscience Center
Affiliations
Research Interests
- Regulation of PXR and CAR (nuclear receptors), and CYP3A (drug–metabolizing enzymes) in drug toxicity, drug resistance and human diseases
- Development of chemical probes and therapeutic leads for PXR, CAR and CYP3A
- Development of drug discovery technologies
- High throughput screening and high content screening
Contact Information
Taosheng Chen, PhD, PMP
Chemical Biology & Therapeutics
MS 1000, Room E9054
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Xiang Chen, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Algorithm development for assessing the interplays between genetic alterations and epigenetic deregulations
- Functional consequences of complex genetic alterations in pediatric solid tumors
- Novel biological discovery from high throughput screening
Contact Information
Xiang Chen, PhD
Computational Biology Department
MS 1135, Room IA6043
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Michael A. Dyer, PhD
Member, St. Jude Faculty
Chair, Developmental Neurobiology Department
Co-Leader, Developmental Biology & Solid Tumor Program
Richard C. Shadyac Endowed Chair in Pediatric Cancer Research
Investigator, Howard Hughes Medical Institute
Michael A. Dyer, PhD
Member, St. Jude Faculty
Chair, Developmental Neurobiology Department
Co-Leader, Developmental Biology & Solid Tumor Program
Richard C. Shadyac Endowed Chair in Pediatric Cancer Research
Investigator, Howard Hughes Medical Institute
Affiliations
Research Interests
- Coordination of proliferation and differentiation during neurogenesis
- Retinal disease and stem cell based therapies
- Retinoblastoma and targeted chemotherapy
- Pediatric solid malignancies
- High throughput screening and drug discovery
- Genomics and epigenomics of pediatric solid tumors
Contact Information
Michael A. Dyer, PhD
Developmental Neurobiology
MS 324, Room D2039
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mark E. Hatley, MD, PhD
Associate Member, St. Jude Faculty
Director, Division of Molecular Oncology
Mark E. Hatley, MD, PhD
Associate Member, St. Jude Faculty
Director, Division of Molecular Oncology
Affiliations
Research Interests
- Cellular and molecular origins of embryonal rhabdomyosarcoma
- MicroRNAs in pediatric sarcomas
- Mouse models of pediatric sarcomas
- Development of novel therapies for pediatric sarcomas
Contact Information
Mark E. Hatley, MD, PhD
Molecular Oncology
MS 354, Room D5048F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Faizan Malik, MD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Morphologic and molecular characterization of bone and soft tissue sarcomas and pediatric solid tumors
- Diagnostic and prognostic biomarkers in solid tumors
- Utilizing novel methodologies for improved pediatric solid tumor classification
Contact Information
Faizan Malik, MD
Pathology
MS 250, Room C5031
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
- Morphologic and molecular characterization of bone and soft tissue sarcomas and pediatric solid tumors
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Anang A. Shelat, PhD
Associate Member, St. Jude Faculty
Director, Lead Discovery Informatics
Anang A. Shelat, PhD
Associate Member, St. Jude Faculty
Director, Lead Discovery Informatics
Affiliations
Research Interests
- Translational research in pediatric cancer
- Development of novel and selective epigenetic drug therapies
- Targeting the DNA damage response to optimize chemo- and radiation therapy
- Multi-scale modeling of biological and chemical data
Contact Information
Anang A. Shelat, PhD
Chemical Biology & Therapeutics
MS 1000, Room E9064
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3578
Pathologists
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Selene Koo, MD, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Diagnosis and classification of pediatric solid tumors
- Histologic and molecular characterization of pediatric solid tumors
Contact Information
Selene Koo, MD, PhD
Pathology
MS 250, Room C5032
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Teresa Santiago, MD
Associate Member, St. Jude Faculty
Director, Coagulation Laboratory
Lead, Global Anatomic Pathology, St. Jude Global
Teresa Santiago, MD
Associate Member, St. Jude Faculty
Director, Coagulation Laboratory
Lead, Global Anatomic Pathology, St. Jude Global
Affiliations
Research Interests
- Laboratory quality improvement and assessment in developing countries
- Coagulopathies
- Solid tumors of childhood
Contact Information
Teresa Santiago, MD
Pathology
MS 250, Room C5030
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Statistician
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Haitao Pan, PhD
Associate Member, St. Jude Faculty
Adjunct Graduate Faculty, Biostatistics, University of Memphis
Adjunct Associate Professor, Florida State University College of Nursing
Haitao Pan, PhD
Associate Member, St. Jude Faculty
Adjunct Graduate Faculty, Biostatistics, University of Memphis
Adjunct Associate Professor, Florida State University College of Nursing
Research Interests
- Bayesian adaptive clinical trials design
- Nonparametric Bayesian modelling
- Digital health
- Longitudinal data analysis
Contact Information
Haitao Pan, PhD
Biostatistics
MS 768, Room R6032
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Clinical scientists
Radiology
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Mary E. (Beth) McCarville, MD
Emeritus, St. Jude Faculty
Affiliations
Research Interests
- Ultrasound
- Contrast Enhanced Ultrasound
- Solid tumor imaging
Contact Information
Mary E. (Beth) McCarville, MD
Department of Radiology
MS 220, Room I3117
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Barry L. Shulkin, MD
Member, St. Jude Faculty
Affiliations
Research Interests
- Use of radioisotopes for the noninvasive detection and management of malignant diseases in childhood
- Use of positron emitting radiotracer probes to characterize the pathophysiology of malignant diseases in childhood
- Application of radiopharmaceuticals as therapeutic agents for malignant diseases in childhood
- Development of new tracers to characterize biologic features of malignant diseases in childhood
- Characterization of the specific type 1 catecholamine uptake process in neuroendocrine tumors
Contact Information
Barry L. Shulkin, MD
Department of Radiology
MS 220, Room I3128
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Radiation therapy
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Matthew J. Krasin, MD
Member, St. Jude Faculty
Affiliations
Research Interests
- Improving radiation target definitions for solid tumors and Hodgkin lymphoma while maintaining local disease control
- Defining the relationships between radiation dose, volume treated and late side effects
- Proton beam radiation
- Radiation late effects
Contact Information
Matthew J. Krasin, MD
Radiation Oncology
MS 210, Room I3122
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Pharmacists
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Melissa S. Bourque, PharmD, BCPS, BCOP
Program Mgr-Pharmacy Specialist
Assistant Professor, The University of Tennessee Health Sciences Center, Department of Clinical Pharmacy and Translational Science
Melissa S. Bourque, PharmD, BCPS, BCOP
Program Mgr-Pharmacy Specialist
Assistant Professor, The University of Tennessee Health Sciences Center, Department of Clinical Pharmacy and Translational Science
Affiliations
Clinical Interests
- Solid Tumor
- Neuro Oncology
- Pain and Palliative Care
- Residency Training
Contact Information
Melissa S. Bourque, PharmD, BCPS, BCOP
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Andy Christensen, PharmD, BCOP
Clinical Pharmacy Specialist
Assistant Professor, The University of Tennessee Health Sciences Center, Department of Clinical Pharmacy and Translational Science
Andy Christensen, PharmD, BCOP
Clinical Pharmacy Specialist
Assistant Professor, The University of Tennessee Health Sciences Center, Department of Clinical Pharmacy and Translational Science
Affiliations
Clinical Interests
- Solid Tumor
- Neuro-oncology
Contact Information
Andy Christensen, PharmD, BCOP
Pharmacy and Pharmaceutical Sciences
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Coordinators
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Joe Brigance, RN, MSN
Solid Tumor Coordinator II
Joe Brigance, RN, MSN
Solid Tumor Coordinator II
Affiliations
Contact Information
Joe Brigance, RN, MSN
Oncology
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Nurse practitoners and physician assistants
Meagan DuLaney, DNP, FNP-C
Advanced Practice Provider
Manager, Solid Tumor/Neuro-Oncology Clinic
Nour McCaffrey, MSN, FNP
Advanced Practice Provider
Ashley McTyre, DNP, FNP-C
Advanced Practice Provider
Sara Meehan, MSN, PNP
Advanced Practice Provider
Carly Meredith, MSN, FNP-BC
Advanced Practice Provider
Manager, Advanced Practice Operations
Patricia Pease, MSN, FNP-BC, RN
APP Professional Development Educator
Alison Rice, MSN, FNP-C
Advanced Practice Provider