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READ: Autonomic Dysfunction in Leukemia/Lymphoma Survivors

About this study

Childhood cancer survivors, particularly those who had leukemia or lymphoma, may develop a condition called cardiac autonomic dysfunction (AD). This condition affects how the heart responds to stress, movement, and other body signals. If AD is not found early, it can lead to serious heart problems.

Right now, patients must visit a doctor to test for AD. This can take a lot of time and may be hard for some people to do. The READ study tests a wrist sensor that could let doctors check for AD without needing a visit. 

For this study, leukemia and lymphoma survivors will go to the doctor for a set of heart tests. These tests will check how the heart reacts to things like deep breathing and standing up quickly. 

After the in-person test, each person will wear a wrist sensor for a week. This device will track their heart rate and changes in heart activity. They will also answer questions about any symptoms they have. Scientists will compare the results from these answers and the wrist sensor with the in-person test to see how accurate the remote method is.

If the wrist device and questionnaire work well, doctors might be able to screen patients for AD remotely to determine which patients may need further in-office testing. This could make it easier for more people to get tested and treated earlier, which might prevent serious heart problems in the future.

Eligibility overview

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Overview

Full title:

Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma

Study goal:

To determine if cardiac autonomic dysfunction can be diagnosed remotely in leukemia and lymphoma survivors

Diagnosis:

Acute lymphoblastic leukemia, Hodgkin lymphoma, Non-Hodgkin lymphoma

Age:

18 years or older

Clinical trials categories:

Childhood Cancer Hodgkin Lymphoma Non-Hodgkin Lymphoma Acute Lymphoblastic Leukemia (ALL)

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

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