St. Jude Children's Research Hospital has an outstanding track record of world-class research and innovation, leading to major scientific advances and ground-breaking new inventions in our mission to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Sometimes, discoveries are made that could be beneficial outside of that mission, and can represent significant opportunities for commercial development.
The Office of Technology Licensing patents inventions with commercial potential and offers them to industry for license. Our goal is to encourage the use of our inventions for the development of products that can be used by researchers and clinicians all over the world, thus benefiting the maximum number of patients. You can explore our technology opportunities for inventions and reagents that are currently available to license.
We are always happy to hear from prospective partners – please contact us if you wish to discuss specific technology interests.
Technologies
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OTL Intellectual Properties Newsletters
The Office of Technology Intellectual Properties Newsletter includes information on the latest technologies licensed and patented by St. Jude Children's Research Hospital as well as contact information for the staff of the Office of Technology Licensing.
Below is a list of all technologies currently available at St. Jude Children's Research Hospital.
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- Activation of Prodrugs by Carboxylesterase (SJ-98-0001)
- Anti-GD2-BB-zeta Chimeric Receptor for Treating GD2+ Malignancies (SJ-13-0035)
- Association of Neuraminidase Regulated Exocytosis with Cancer Metastasis (SJ-11-0012)
- BCRP/ABCG2 as Stem Cell Marker (SJ-97-0016)
- Development and Optimization of a Serotype-Independent Method of Adeno-Associated Virus (AAV) Harvest and Purification (SJ-16-0036)
- DNA Methylation Profile and Biomarkers for identifying functional T-cells (SJ-17-0002)
- Gene Therapy for XSCID (SJ-16-0006)
- Hybrid Compounds to treat Gastrointestinal Infections (SJ-14-0019/UTA 14-01)
- Improved Method to Produce Proteins to Treat Lysosomal Storage Disorders (SJ-01-0020)
- iNKT Cell Expansion Protocol (SJ-12-0033)
- Method for Enhancing Recombinant Antibody Production (SJ-08-0032)
- Minimized Liver Specific Promoter for Improved Gene Expression in Gene Therapy Vectors (SJ-04-0024)
- p53 Inhibitory Oligonucloeotides (SJ-09-0015)
- Rapid Cloning of T Cell Receptors (SJ-16-0001)
- Regulating p53 Translation and Function (SJ-05-0002)
- RIPK3 Fusion Protein for Treating Cancer and Autoimmunity (SJ-12-0036)
- Use of IL35 to convert T-cells to Regulatory T-cells (SJ-09-0024)
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- A Novel Method for Quantitative Detection of Purines and Their Metabolites (SJ-13-0014)
- Association of Neuraminidase Regulated Exocytosis with Cancer Metastasis (SJ-11-0012)
- Genotyping Assay to Predict CYP3A5 Phenotype (SJ-01-0005)
- Human Multidrug Resistance Protein 4 (MRP4) (SJ-98-0013)
- Medulloblastoma Subtyping Assay (SJ-10-0020)
- Methods for Diagnosing and Treating Learning or Mental Disorders with the SERCA2 Protein and miRNAs that regulate SERCA2 Levels (SJ-10-0003 and SJ-12-0020)
- New Markers for Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia (SJ-11-0025)
- Prediction of MRD in Leukemia Patients (SJ-14-0012)
- Rapid Cloning of T Cell Receptors (SJ-16-0001)
- SNPs in suppressor of fused (SUFU) associated with acute GVHD (SJ-14-0018)
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- Compounds for Treatment of BCR-ABL + Lymphoblastic Leukemias (using an existing malaria drug to overcome resistance) (SJ-11-0042)
- DON and small molecule Bcl-2 family antagonists treating glutamine addicted cell lines for Neuroblastomas and Ewing sarcomas (SJ-13-0026)
- Hybrid Compounds to treat Gastrointestinal Infections (SJ-14-0019/UTA 14-01)
- Improved Human Carboxylesterase for Therapy with CPT-11 (SJ-06-0006)
- Method for Improving Learning and Treating Neurological Diseases (SJ-15-0009)
- Methods and compositions for the prevention and treatment of hearing loss using CDK2 inhibitors (SJ-14-0028)
- Methods for Diagnosing and Treating Learning or Mental Disorders with the SERCA2 Protein and miRNAs that regulate SERCA2 Levels (SJ-10-0003 and SJ-12-0020)
- New Uses for Chloroquine and Chloroquine Analogs (SJ-02-0008 and SJ-05-0017)
- Novel Carboxylesterase Inhibitors (SJ-02-0030)
- Sudemycins: Synthetic Natural Product Analogs as Anti-Cancer Agents (SJ-08-0026 & SJ-13-0007)
- Thalamic microRNA controls the late onset of schizophrenia (SJ-15-0035)
- Therapeutic Leads Targeting Influenza Endonuclease (SJ-09-0041)
- Treating Cochlear Hearing loss with p27Kip1/Atoh1 Combinations (SJ-13-0019)
- Use of metabolic drugs to treat influenza infection (SJ-14-0040)
- Use of small molecule ER stress modulators to treat tumors with active Sonic Hedgehog (SHH) signaling due to Smoothened (SMO) mutation (SJ-12-0038)
- Use of specific retinoid receptor agonists and antagonists as cancer therapies (SJ-14-0011)
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- Activation of Prodrugs by Carboxylesterase (SJ-98-0001)
- Alternate mTOR Pathway (SJ-09-0021)
- ARF and HDM2 interaction domains (SJ-01-0016)
- Assay for ATM Kinase Modulation (SJ-02-0008)
- Caspase 1 inhibition to overcome glucocorticoid resistance (SJ-13-0039)
- Cells That Lack p19Ink4d and p27Kip1 Activity/p19Ink4d and p27Kip1 Null Mice (SJ-98-0023)
- Defects in LC3-associated phagocytosis (LAP) associated with Lupus (SJ-16-0025)
- Discovery of a fluorescent vinblastine analog with high affinity to the human pregnane X receptor (hPXR) Ligand (SJ-13-0009)
- Discovery of a novel inhibitor of constitutive androstane receptor (CAR) that does not activate pregnane X receptor (PXR) (SJ-14-0039)
- DON and small molecule Bcl-2 family antagonists treating glutamine addicted cell lines for Neuroblastomas and Ewing sarcomas (SJ-13-0026)
- Hematopoietic progenitor cell lines with myeloid and lymphoid potential (SJ-11-0003)
- Human Multidrug Resistance Protein 4 (MRP4) (SJ-98-0013)
- Interaction of Reelin With Very Low Density Lipoprotein (VLDL) Receptor (SJ-98-0045)
- Method for Enhancing Recombinant Antibody Production (SJ-08-0032)
- Methods and compositions for the prevention and treatment of hearing loss using CDK2 inhibitors (SJ-14-0028)
- Methods for Diagnosing and Treating Learning or Mental Disorders with the SERCA2 Protein and miRNAs that regulate SERCA2 Levels (SJ-10-0003 and SJ-12-0020)
- Ozz, A Protein That Regulates Development and Function of Muscle Cells (SJ-99-0010)
- Rapid Cloning of T Cell Receptors (SJ-16-0001)
- Regulating p53 Translation and Function (SJ-05-0002)
- SCCRO Peptide Inhibitor (SJ-11-0014)
- SNPs in suppressor of fused (SUFU) associated with acute GVHD (SJ-14-0018)
- Use of specific retinoid receptor agonists and antagonists as cancer therapies (SJ-14-0011)
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- General Architecture for Defining and Collecting Data (SJ-03-0005)
- Multi-slice Myelin Water Imaging (SJ-12-0009)
- Phase Cycled Magnetic Resonance Spectroscopic Imaging (SJ-15-0032)
- ProteinPaint: Web Application for Visualizing Genomic Data (SJ-15-0021)
- System Design and Method for Verifying 3D Dosimetric Imaging (SJ-15-0022)
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- Attenuated Streptococcus Pneumoniae Strain and Vaccine for Protection Against Pneumococcal Disease (SJ-11-0001)
- Avian Influenza Vaccine (SJ-06-0013)
- Group B Streptococcus (GBS) Extracellular Matrix Adhesion Proteins (SJ-00-0030)
- Improved System for Generating Human Influenza Vaccine in Cell Tissue Culture (SJ-02-0016)
- Methods and Composition for Diagnosing and Preventing a Group B Streptococcal Infection (SJ-02-0032)
- Modified Influenza Virus for Monitoring and Improving Vaccine Efficiency (SJ-04-0033)
- Modified Sendai Virus Vaccine and Imaging Vector (SJ-11-0018)
- Reverse Genetics System for Generating RNA Viruses and Vaccines (SJ-00-0006)
- Synthetic Vaccine and Immunogenic Fusion Proteins for Pneumococcal Infections, and uses (SJ-05-0036, SJ-10-0028, SJ-13-0032)
- Universal Influenza Vaccine (SJ-05-0040)