The faculty below conduct laboratory- and behavior-based research at St. Jude Children's Research Hospital.
Biostatistics
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Cheng Cheng, PhD
Cheng
Statistical methods in cancer genomics and genetics
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Meenakshi Devidas, PhD, MBA
Devidas
Pediatric hematology and oncology; clinical trial design; survival analysis
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Guolian Kang, PhD
Kang
Statistical genetics/genomics, statistical modeling of complex data
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Cai Li, PhD
Li
Statistical learning and computing methods for neurodegeneration
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Causal inference, survival analysis, cancer survivorship
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Qian Li, PhD
Li
High-dimensional multi-omics, longitudinal modeling, statistical learning
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Statistical analysis of complex imaging data
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Sedigheh Mirzaei, PhD
Mirzaei
Develop theory and applied statistical methods for imperfectly recalled survival data
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Basic, translational, clinical and population science
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Arzu Onar-Thomas, PhD
Onar-Thomas
Phase I-II designs, survival analysis, Bayesian statistics
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Haitao Pan, PhD
Pan
Develop Bayesian adaptive designs for Phase I-II clinical trials
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Stan Pounds, PhD
Pounds
Develop statistical methods for genomics studies
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Subodh Selukar, PhD
Selukar
Design and analysis of clinical trials, survival analysis with long-term survivors
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Deo Kumar Srivastava, PhD
Srivastava
Clinical trials, robust methods, survival analysis, goodness-of-fit tests
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Li Tang, PhD
Tang
Measurement error and classification, longitudinal modeling, complex epidemiologic study design
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Yiwang Zhou, PhD
Zhou
Develop statistical methods for precision medicine studies
Bone Marrow Transplant & Cellular Therapy
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Senthil Bhoopalan, MBBS, PhD, FAAP
Bhoopalan
Gene therapy for blood disorders
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Christopher DeRenzo, MD, MBA
DeRenzo
Immunotherapy for patients with solid tumors
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Stephen Gottschalk, MD
Gottschalk
Cancer immunotherapy, cell therapy, stem cell transplantation
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Giedre Krenciute, PhD
Krenciute
CAR T-cell immunotherapy for brain tumors
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Paulina Velasquez, MD
Velasquez
Immunotherapy for hematological malignancies
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Caitlin Zebley, MD, PhD
Zebley
Fundamental mechanisms of T cell biology
Cell & Molecular Biology
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Chi-Lun Chang, PhD
Chang
Dynamic regulation of inter-organelle communication
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Bryan A. Gibson, PhD
Gibson
Organization of chromosomes through phase separation
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Mondira Kundu, MD, PhD
Kundu
Autophagy and relevance to human disease
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Peter J. McKinnon, PhD
McKinnon
DNA damage responses in the nervous system
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Heather C. Mefford, MD, PhD
Mefford
Genetics of pediatric neurological disease
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Stacey K. Ogden, PhD
Ogden
Mechanisms of Hedgehog signal transduction
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Joseph T. Opferman, PhD
Opferman
Regulation of cell death during hematopoiesis
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Shondra Pruett-Miller, PhD
Pruett-Miller
Genome-editing technologies
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J. Paul Taylor, MD, PhD
Taylor
Molecular genetics of neurological disease
Chemical Biology & Therapeutics
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Aseem Z. Ansari
Ansari
Synthetic genome regulators
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Daniel J. Blair, PhD
Blair
Covalent interactions between small molecules and proteins/RNA
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Small-molecule transcription factor drug discovery
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Tommaso Cupido, PhD
Cupido
Chemical biology of protein machines
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Hai T. Dao, PhD
Dao
Chromatin dynamics during transcription
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Marcus Fischer, PhD
Fischer
Exploiting the protein conformational landscape for ligand discovery
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Development of new chemotherapeutic agents
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Anang A. Shelat, PhD
Shelat
Multi-scale modeling of biological and chemical data
Computational Biology
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Brian J. Abraham, PhD
Abraham
Transcriptional control of cell identity and disease
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Xiang Chen, PhD
Chen
OMICS integration and tumor heterogeneity by machine learning approaches
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Paul Geeleher, PhD
Geeleher
Computational methods and drug repositioning
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Mathematical modeling of cancer initiating events
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Systems biology, functional genomics and immuno-oncology
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Jinghui Zhang, PhD
Zhang
Genomic sequence analysis and visualization
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Xin Zhou, PhD
Zhou
Multi-omics and biomedical data visualization
Developmental Neurobiology
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Suzanne J. Baker, PhD
Baker
Molecular, cellular and developmental pathogenesis of pediatric high-grade glioma
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Jay B. Bikoff, PhD
Bikoff
Functional organization of spinal interneurons
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Xinwei Cao, PhD
Cao
Growth control during neural tube development
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Fabio Demontis, PhD
Demontis
Mechanisms of skeletal muscle aging, protein homeostasis, and myokines
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Michael Dyer, PhD
Dyer
Retinal development and retinoblastoma
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Regulatory mechanisms of neural progenitors in brain development, diseases, & evolution
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Khaled Khairy, PhD
Khairy
Computational models of membrane-bound structures, and priors in biological image analysis
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Stephen C. Mack, PhD
Mack
Pediatric brain tumors; cancer epigenetics; therapeutics; models
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James I. Morgan, PhD
Morgan
Control of neuronal death and differentiation
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Paul A. Northcott, PhD
Northcott
Integrative genomics and molecular features of pediatric brain tumors
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Jamy C. Peng, PhD
Peng
Epigenetic regulation of stem cell functions
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Junmin Peng, PhD
Peng
Proteomics to ubiquitin biology and human disease
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Jasmine Plummer, PhD
Plummer
Spatial Omics
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Lindsay Schwarz, PhD
Schwarz
Molecular and organizational diversity of neuromodulatory circuits and their role in neuropsychiatric disease
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David J. Solecki, PhD
Solecki
Cell polarity in neuron precursor differentiation
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Jason D. Vevea, PhD
Vevea
Molecular mechanisms of the synaptic vesicle cycle
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Stanislav S. Zakharenko, MD, PhD
Zakharenko
Neural circuits of learning, memory and their dysfunction in neuropsychiatric disease
Diagnostic Imaging
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Response assessment of immunotherapy and radiation therapy
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Puneet Bagga, PhD
Bagga
Molecular MRI and MR spectroscopic techniques
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Kiel Neumann, PhD
Neumann
Translational Imaging; radiopharmaceutical development
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Wilburn E. Reddick, PhD
Reddick
White matter injury and neurocognitive functioning
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Ranganatha Sitaram, ME, PhD
Sitaram
Multimodal functional brain imaging and neurorehabilitation
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Andrew D. Smith, MD, PhD
Smith
Epidemiology & Cancer Control
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Greg Armstrong, MD, MSCE
Armstrong
Pediatric neuro-oncology and cancer survivorship
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Heather M. Brandt, PhD
Brandt
HPV vaccination; implementation science; partnered and engaged research
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Joshua Burns, PhD
Burns
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I-Chan Huang, PhD
Huang
Patient-reported outcomes measurement for childhood cancer
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Functional limitations among cancer survivors
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Yadav Sapkota, PhD
Sapkota
Genomic basis of pediatric cancer outcomes
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Zhaoming Wang, PhD
Wang
Genetic epidemiology of pediatric cancer and survivorship
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Carmen Wilson, PhD
Wilson
Late effects of childhood cancer therapy
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Yutaka Yasui, PhD
Yasui
Genetics and risk of therapy-related outcomes
Genetics
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Alessandra d'Azzo, PhD
d'Azzo
Intracellular degradation in development and disease
Global Pediatric Medicine
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Asya Agulnik, MD, MPH
Agulnik
Global pediatric health, hospital quality of care, critical care in pediatric oncology, and clinical prediction scores
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Nickhill Bhakta, MD, MPH
Bhakta
Global pediatric medicine
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Miguela Caniza, MD, MPH
Caniza
Infectious Diseases International Outreach
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Meenakshi Devidas, PhD, MBA
Devidas
Pediatric hematology and oncology; clinical trial design; survival analysis
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Paola Friedrich, MD, MPH
Friedrich
Global pediatric oncology; clinical effectiveness; health disparities; pediatric solid tumors
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Sima Jeha, MD
Jeha
Childhood leukemias, developmental therapeutics
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International outreach, rare tumors, treatment adherence
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Daniel Moreira, MD, MEd
Moreira
Global pediatric oncology; evidence-based education; pediatric CNS tumors
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Sheena Mukkada, MD, MPH
Mukkada
Infectious diseases, global health
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Ibrahim Qaddoumi, MD, MS
Qaddoumi
Low grade gliomas, global health, telemedicine and retinoblastoma
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Carlos Rodriguez-Galindo, MD
Rodriguez-Galindo
Global medicine; pediatric solid tumors
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Jeremy Slone, MD, MPH
Slone
Global pediatric cancer epidemiology
Hematology
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Yong Cheng, PhD
Cheng
Genomic approaches to studying cis-regulatory modules in hematopoiesis
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Wilson K. Clements, PhD
Clements
Vascular/hematopoietic development and leukemia
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John D. Crispino, PhD, MBA
Crispino
Inherited and acquired blood disorders
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Marta Derecka, PhD
Derecka
Bone marrow niche function in hematopoiesis
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Alyssa Lee Kennedy, MD, PhD
Kennedy
Inherited Bone Marrow Failure Disorders
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Dirk Loeffler, PhD
Loeffler
Cancer stem cells & clonal hematopoiesis
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Shannon McKinney-Freeman, PhD
McKinney-Freeman
Cellular and molecular regulation of hematopoietic stem cell in vivo repopulating activity, hematopoietic stem cell development and specification
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Advancing genome editing and protein engineering technologies for therapeutics
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Blood development and associated diseases
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Marcin Wlodarski, MD, PhD
Wlodarski
Inherited bone marrow failure and MDS predisposition syndromes
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Novel genome engineering strategies to treat hemoglobinopathies
Host-Microbe Interactions
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Julia L. Hurwitz, PhD
Hurwitz
Pathology/vaccine-induced immunity, nuclear hormones
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Jason W. Rosch, PhD
Rosch
Bacterial genomics and pathogenesis
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Charles J. Russell, PhD
Russell
Respiratory viruses: disease, cures & prevention
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Stacey L. Schultz-Cherry, PhD
Schultz-Cherry
Pathogenesis of influenza and enteric virus infections
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Paul G. Thomas, PhD
Thomas
Innate and adaptive immunity to influenza
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Victor J. Torres, PhD
Torres
Bacterial pathogenesis and host response to infection
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Elaine I. Tuomanen, MD
Tuomanen
Pathogenesis of pneumococcal infection
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Richard J. Webby, PhD
Webby
Influenza virus pathogenicity
Immunology
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Hongbo Chi, PhD
Chi
Cellular signaling in innate and adaptive immunity
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Yongqiang Feng, PhD
Feng
Transcriptional and epigenetic basis of T cell biology
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Douglas R. Green, PhD
Green
Apoptosis, autophagy and mitochondria
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Bo Hu, PhD
Hu
Investigating Neuro-Immune Interactions in Health and Disease
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Thirumala-Devi Kanneganti, PhD
Kanneganti
Mechanisms of host defense and inflammation
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Paul G. Thomas, PhD
Thomas
Innate and adaptive immunity to influenza
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Benjamin A. Youngblood, PhD
Youngblood
T cell memory differentiation and exhaustion
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Yunlong Zhao, PhD
Zhao
Unraveling the immune receptor networks in T cell anti-tumor immunity
Infectious Diseases
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Ellie Margolis, MD, PhD
Margolis
Microbiome dynamics in immunocompromised patients and infants
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Viral respiratory and perinatal infections
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Octavio Ramilo, MD
Ramilo
Viral respiratory infections, early life immunity
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Steven M. Varga, PhD
Varga
Immunity and pathogenesis of respiratory viruses
Oncology
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Greg Armstrong, MD, MSCE
Armstrong
Pediatric neuro-oncology and cancer survivorship
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Adam D. Durbin, MD, PhD
Durbin
Transcriptional and epigenetic control in neuroblastoma
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Lillian Macrae Guenther, MD
Guenther
Pediatric bone sarcomas
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Mark E. Hatley, MD, PhD
Hatley
Cellular and molecular origins of rhabdomyosarcoma
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Myriam Labelle, PhD
Labelle
The role of the microenvironment in cancer metastasis
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Min Ni, PhD
Ni
Metabolism in development and cancer
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Kim E. Nichols, MD
Nichols
Heritable cancers and primary immunodeficiency syndromes
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Esther A. Obeng, MD, PhD
Obeng
Myeloid malignancies and bone marrow failure syndromes
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Anand Patel, MD, PhD
Patel
Tumor recurrence in pediatric rhabdomyosarcoma
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Charles W. M. Roberts, MD, PhD
Roberts
SWI/SNF (BAF) chromatin remodeling/tumor suppressor
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Elizabeth A. Stewart, MD
Stewart
High risk pediatric solid tumors
Pathology
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James R. Downing, MD
Downing
The molecular pathology of acute leukemia
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Terrence L. Geiger, MD, PhD
Geiger
Immune system regulation and autoimmunity
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Genomic and functional characterization of acute myeloid leukemia
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Genomics, experimental modeling and preclinical therapeutics of acute leukemia
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Gang Wu, PhD
Wu
Genome instability, neurodegeneration, brain transcriptomics
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Jian Xu, PhD
Xu
Regulation of normal and malignant hematopoiesis
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Gerard P. Zambetti, PhD
Zambetti
p53 function in tumor suppression & tumorigenesis
Pharmacy and Pharmaceutical Sciences
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Pharmacogenomics, pharmacoepidemiology, and outcomes research
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Samuel W. Brady, PhD
Brady
Cancer vulnerabilities arising from genomic alterations
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Markos Leggas, PhD
Leggas
Pharmacometabolomic and pharmacometric approaches to tailor therapy
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Understanding antibiotic resistance and persistence using bacterial single-cell transcriptomics
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Molecular and genetic basis of antifungal pharmacotherapy
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Development, enhancement, and preservation of antifungal pharmacotherapy
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Daniel Savic, PhD
Savic
Pharmacogenomics and cis-regulatory architecture of pediatric leukemia
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John D. Schuetz, PhD
Schuetz
ABC transporters and mitochondrial biology
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Clinton F. Stewart, PharmD
Stewart
Pharmacokinetics and anticancer drug development
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Jun J. Yang, PhD
Yang
Pharmacogenomics of anticancer agents and drug resistance
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Liqin Zhu, PhD
Zhu
Stem cells in normal and malignant development
Psychology and Biobehavioral Science
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Tara M. Brinkman, PhD
Brinkman
Psychosocial outcomes of childhood cancer
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Heather Conklin, PhD
Conklin
Improving cognitive outcomes for childhood cancer survivors
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Valerie Crabtree, PhD
Crabtree
Sleep disruption and fatigue in children and youth with cancer
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Ashley S. Fournier-Goodnight, PhD, ABPP-CN
Fournier-Goodnight
Neurobehavioral outcomes in infants and toddlers with early brain pathology, central nervous system directed therapy and rare neurodevelopmental/neurogenetic disorders; neurobehavioral assessment of infants and toddlers with acute neurologic injury
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Andrew Heitzer, PhD, ABPP-CN
Heitzer
Neurocognitive outcomes in sickle cell disease
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Lisa Jacola, PhD, ABPP-CN
Jacola
Neurobehavioral outcomes in children treated for cancer
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Ryan N. James, PhD
James
Pediatric pain from a biopsychosocial perspective
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Kevin R. Krull, PhD
Krull
Neurocognitive outcomes of pediatric cancer
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Nicholas Phillips, MD, PhD
Phillips
Neurocognitive late effects; cancer survivorship; functional and structural neuroimaging
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Jerlym S. Porter, PhD, MPH
Porter
Health management and transition to adult care in sickle cell disease
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Brian Potter, PsyD
Potter
Neurocognitive outcomes in children with cancer
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Darcy Raches, PhD
Raches
Acute neurological injury and cognitive outcomes associated with childhood cancer treatment
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Katianne Sharp, PhD
Sharp
Cancer predisposition and adjustment in families of children with cancer
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Rachel Tillery Webster, PhD
Tillery Webster
Promotion of healthy lifestyle behaviors in children with cancer and survivors of childhood cancer
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Rachel Tillery Webster, PhD
Webster
Promotion of healthy lifestyle behaviors in children with cancer and survivors of childhood cancer
Radiation Oncology
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Chia-ho Hua, PhD
Hua
Image-guided proton therapy, late effects, predictive radiation therapy
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Matthew J. Krasin, MD
Krasin
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Brain tumors, neuroblastoma, proton therapy, clinical trial design
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Thomas E. Merchant, DO, PhD
Merchant
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Christopher Tinkle, MD, PhD
Tinkle
Molecular mechanisms governing ionizing radiation response/resistance
Structural Biology
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Data science for discovery and personalized medicine
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Scott C. Blanchard, PhD
Blanchard
Examining structure-function relationships in macromolecular assemblies
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Mario Halic, PhD
Halic
Regulation of genome expression
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Charalampos Kalodimos, PhD
Kalodimos
Functional mechanisms of protein machineries
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Elizabeth H. Kellogg, PhD
Kellogg
Genome engineering, organization, and architecture
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Richard W. Kriwacki, PhD
Kriwacki
Structural basis of tumor suppressor function
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Molecular mechanisms of membrane signaling complexes
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Tanja Mittag, PhD
Mittag
Dynamic protein complexes in signal transduction
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Junmin Peng, PhD
Peng
Proteomics to ubiquitin biology and human disease
Surgery
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Andrew M. Davidoff, MD
Davidoff
Neuroblastoma, renal tumors, and germ cell tumors; angiogenesis inhibition for cancer therapy
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Andrew Jackson Murphy, MD
Murphy
Renal tumors, neuroblastoma, Wilms tumorigenesis, cancer stem cells
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Jun Yang, MD, PhD
Yang
Cancer epigenetics and targeted therapy
Tumor Cell Biology
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Genome editing in cancer development
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Martine F. Roussel, PhD
Roussel
Pediatric brain tumors: molecular pathways, mouse models, and pre-clinical trials
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Tumor suppressor–dependent signaling networks